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Location： Home > Recombinant Rabbit Monoclonal Antibodies > IKK gamma Rabbit mAb

IKK gamma Rabbit mAb#49550

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Product Detail

Product NameIKK gamma Rabbit mAb

Clone No.JA11-83

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, ICC/IF, IP, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesIkB kinase associated protein 1 antibody
IkB kinase subunit gamma antibody
Inhibitor of nuclear factor kappa B kinase subunit gamma antibody
AMCBX1 antibody
FIP 3 antibody
FIP-3 antibody
FIP3 antibody
Fip3p antibody
I kappa B kinase gamma antibody
I-kappa-B kinase subunit gamma antibody
IkB kinase gamma subunit antibody
IkB kinase subunit gamma antibody
IkB kinase-associated protein 1 antibody
Ikbkg antibody
IKK-gamma antibody
IKKAP1 antibody
IKKG antibody
IMD33 antibody
Incontinentia pigmenti antibody
Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma antibody
Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma antibody
Inhibitor of nuclear factor kappa-B kinase subunit gamma antibody
IP antibody
IP1 antibody
IP2 antibody
IPD2 antibody
NEMO antibody
NEMO_HUMAN antibody
NF kappa B essential modifier antibody
NF kappa B essential modulator antibody
NF-kappa-B essential modifier antibody
NF-kappa-B essential modulator antibody
ZC2HC9 antibody

Accession NoSwiss-Prot#:Q9Y6K9

Uniprot Q9Y6K9

Gene ID 8517;

Calculated MW48 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:20-1:50
ICC: 1:50-1:200

FC: 1:50-1:100
Western blot analysis of IKK gamma on Hela cell using anti-IKK gamma antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse fallopian tube tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
ICC staining IKK gamma in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of Hela cells with IKK gamma antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.

If you have published an article using product 49550, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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