Product Detail
Product NameLipoprotein lipase Rabbit mAb
Clone No.JA22-02
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesEC 3.1.1 antibody
EC 3.1.1.34 antibody
HDLCQ11 antibody
LIPD antibody
LIPL_HUMAN antibody
Lipoprotein lipase antibody
LPL antibody
LPL protein antibody
MGC137861 antibody
Accession NoSwiss-Prot#:P06858
Uniprot
P06858
Gene ID
4023;
Calculated MW53 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200
Western blot analysis of Lipoprotein lipase on human placenta tissue lysate using anti-Lipoprotein lipase antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human ileum tissue using anti-Lipoprotein lipase antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Lipoprotein lipase antibody. Counter stained with hematoxylin.
The Lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Members of the AB hydrolase subfamily include hepatic lipase (HL), endothelial lipase (EL), lipoprotein lipase (LPL) and pancreatic lipase (PL). HL balances the composition and transport of lipoproteins in human plasma. Synthesized in endothelial cells, EL hydrolyzes high density lipoproteins. LPL, a homodimer attached to the membrane by a GPI-anchor, mediates the hydrolysis of triglycerides of very low density lipoproteins and circulating chylomicrons. Defects in LPL may cause chylomicronemia syndrome or a form of lipoprotein lipase deficiency characterized by hypertriglyceridemia.
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