Product Detail
Product NameMEF2A Rabbit mAb
Clone No.JA33-04
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesADCAD1 antibody
MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody
MEF2 antibody
MEF2A antibody
MEF2A_HUMAN antibody
Myocyte enhancer factor 2A antibody
Myocyte-specific enhancer factor 2A antibody
RSRFC4 antibody
RSRFC9 antibody
Serum response factor like protein 1 antibody
Serum response factor-like protein 1 antibody
Accession NoSwiss-Prot#:Q02078
Uniprot
Q02078
Gene ID
4205;
Calculated MW54 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
IHC: 1:50-1:200
ICC: 1:50-1:200
Western blot analysis of MEF2A on rat spleen tissue lysate using anti-MEF2A antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse cerebral cortex tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse hippocampus tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
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