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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Glucose Transporter GLUT3 Rabbit mAb

Glucose Transporter GLUT3 Rabbit mAb#49567

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Product Detail

Product NameGlucose Transporter GLUT3 Rabbit mAb

Clone No.JA50-31

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB; FC

Species ReactivityHu, Ms, Rt

Immunogen TypePeptide

Immunogen DescSynthetic peptide within Human GLUT3

ConjugateUnconjugated

Other Namesbrain antibody
FLJ90380 antibody
Glucose transporter type 3 antibody
Glucose transporter type 3 brain antibody
GLUT 3 antibody
GLUT-3 antibody
GLUT3 antibody
GTR3_HUMAN antibody
Slc2a3 antibody
Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody
Solute carrier family 2, facilitated glucose transporter member 3 antibody

Accession NoSwiss-Prot#:P11169

Uniprot P11169

Gene ID 6515;

Calculated MW54 kDa

Formulation1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB 1:5000
FC 1:50-1:100

Flow cytometric analysis of SH-SY5Y cells with Glucose Transporter GLUT3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Western blot analysis of Glucose Transporter GLUT3 on different lysates with GLUT3 antibody at 1/5000 dilution.
Lane 1: HepG2 cell lysate (20 µg/Lane)
Lane 2: RAW264.7 cell lysate (20 µg/Lane)
Lane 3: C6 cell lysate (20 µg/Lane)
Lane 4: Mouse brain tissue lysate (20 µg/Lane)
Lane 5: Rat brain tissue lysate (20 µg/Lane)
Predicted band size: 54 kDa
Observed band size: 54 kDa

Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, Insulin stimulates a rapid and dramatic increase in glucose uptake, largely due to the redistribution of the Insulin-inducible glucose transporter, Glut4. In response to Insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to Insulin. Glut2 expression is seen in pancreatic b cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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