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Location： Home > Recombinant Rabbit Monoclonal Antibodies > TXNRD1 Rabbit mAb

TXNRD1 Rabbit mAb#49585

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Product Detail

Product NameTXNRD1 Rabbit mAb

Clone No.JA11-32

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC, IHC, IP, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other Namescytoplasmic antibody
Gene associated with retinoic and IFN-induced mortality 12 protein antibody
Gene associated with retinoic and interferon-induced mortality 12 protein antibody
Gene associated with retinoid IFN induced mortality 12 protein antibody
GRIM 12 antibody
GRIM-12 antibody
GRIM12 antibody
KDRF antibody
KM 102 derived reductase like factor antibody
KM-102-derived reductase-like factor antibody
MGC9145 antibody
Oxidoreductase antibody
Thioredoxin reductase 1 antibody
Thioredoxin reductase 1 cytoplasmic antibody
Thioredoxin reductase GRIM 12 antibody
Thioredoxin reductase TR1 antibody
TR 1 antibody
TR antibody
TR1 antibody
TRXR 1 antibody
TRXR1 antibody
TRXR1_HUMAN antibody
TXNR antibody
TXNRD 1 antibody
Txnrd1 antibody

Accession NoSwiss-Prot#:Q16881

Uniprot Q16881

Gene ID 7296;

Calculated MW55 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100
Western blot analysis of TXNRD1 on Hela (1) and human liver tissue lysate (2) using anti-TXNRD1 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TXNRD1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse testes tissue using anti-TXNRD1 antibody. Counter stained with hematoxylin.
ICC staining TXNRD1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of SH-SY5Y cells with TXNRD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx reductases (TrxR1 and TrxR2) are ubiquitous Ly noble flavoproteins that catalyze the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. Mammalian Trx reductases are a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val- Asn-Val-Gly-Cys. TrxR1 and TrxR2 are also involved in the prevention of oxidative stress. Inhibition of TrxR activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.

If you have published an article using product 49585, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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