Product Detail
Product NamePKC beta 1 Rabbit mAb
Clone No.JM43-26
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, FC
Species ReactivityHu, Ms, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesBTN6 antibody
BTNL11 antibody
MGC26137 antibody
MOG alpha 5 antibody
MOG alpha 6 antibody
MOG AluA antibody
MOG AluB antibody
MOG antibody
MOG Ig AluB antibody
MOG_HUMAN antibody
MOGIG2 antibody
Myelin oligodendrocyte glycoprotein antibody
Myelin-oligodendrocyte glycoprotein antibody
NRCLP7 antibody
Accession NoSwiss-Prot#:P05771
Uniprot
P05771
Gene ID
5579;
Calculated MW77 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
IHC: 1:50-1:200
FC: 1:50-1:100
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoformsandν. Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
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