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CD79a Rabbit mAb#52209

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Product Detail

Product NameCD79a Rabbit mAb

Clone No.S02-7E3

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity Purified

ApplicationsWB IHC

Species ReactivityHuman

Immunogen DescA synthetic peptide of human CD79a

ConjugateUnconjugated

Other NamesIGA; MB-1

Accession NoSwiss-Prot:P11912
GeneID:973

Uniprot P11912

Gene ID 973

Calculated MWCalculated MW: 25 kDa; Observed MW: 45-55 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1/1000-1/2000; IHC: 1/20-1/50;
Western blot detection of CD79a in Jurkat cell lysates using CD79a Rabbit mAb(1:500 diluted).Predicted band size:25kDa.Observed band size:45-55kDa.
Immunohistochemistry of CD79a in paraffin-embedded Human tonsil using CD79a Rabbit mAb at dilution 1/50
Swiss-Prot Acc.P11912.Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

If you have published an article using product 52209, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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