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CD105 Rabbit mAb#52734

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Product Detail

Product NameCD105 Rabbit mAb

Clone No.S05-3H7

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeIgG

PurificationAffinity Purified

ApplicationsWB IHC

Species ReactivityHuman

Immunogen DescRecombinant protein of human CD105

ConjugateUnconjugated

Other NamesCD105; END; Endoglin; Eng; HHT1; ORW; ORW1; SN6;

Accession NoSwiss-Prot:P17813
GeneID:2022

Uniprot P17813

Gene ID 2022

Calculated MWCalculated MW:71 kDa,Observed MW:95 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1/1000 IHC: 1/20
Western blot detection of CD105 in Hela,A549 cell lysates using CD105 Rabbit mAb(1:1000 diluted).Predicted band size:71kDa.Observed band size:95kDa.
Immunohistochemistry of CD105 in paraffin-embedded Human lung cancer tissue using CD105 Rabbit mAb at dilution 1/50
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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