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Location： Home > Polyclonal Antibodies > NOD2 Rabbit Polyclonal Antibody

NOD2 Rabbit Polyclonal Antibody#54121

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Product NameNOD2 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human NOD2 (NP_071445.1).

ConjugateUnconjugated

Other NamesNOD2;ACUG;BLAU;BLAUS;CARD15;CD;CLR16.3;IBD1;NLRC2;NOD2B;PSORAS1;YAOS

Accession NoUniprot:Q9HC29
GeneID:64127

Uniprot Q9HC29

Gene ID 64127

Calculated MW22kDa/112kDa/115kDa

Sdspage MW100KDa

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using NOD2 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human colon using NOD2 Rabbit pAb.
Immunofluorescence analysis of HeLa cells using NOD2 Rabbit pAb.
Immunofluorescence analysis of PC-12 cells using NOD2 Rabbit pAb.
Immunofluorescence analysis of NIH/3T3 cells using NOD2 Rabbit pAb.
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

If you have published an article using product 54121, please notify us so that we can cite your literature.

et al,Pyroptosis-associated genes and tumor immune response in endometrial cancer. In Discov Oncol on 2024 Sep 12 by Xiaodi Gong, Zhifeng Wang,et al..PMID:39264524 , (2024),
PMID: 39264524
et al,H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes. , (2025),
PMID: 40075479

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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