Product Detail
Product NameCXCL12 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant protein of human CXCL12.
ConjugateUnconjugated
Other NamesCXCL12;IRH;PBSF;SCYB12;SDF1;TLSF;TPAR1
Accession NoUniprot:P48061
GeneID:6387
Uniprot
P48061
Gene ID
6387
Calculated MW11kDa
Sdspage MW11kDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using CXCL12 antibody.
Immunohistochemistry of paraffin-embedded human gastric cancer using CXCL12 Rabbit pAb.
Immunofluorescence analysis of human liver cells using CXCL12 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human tonsil using CXCL12 Rabbit pAb.
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
If you have published an article using product 54506, please notify us so that we can cite your literature.
et al,Relationship between surrounding tissue morphology and directional collective migration of the posterior lateral line primordium in zebrafish
, (2020),
PMID:
32516841