Product Detail
                                
                                                                        Product NameATP1A1 Rabbit Polyclonal Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC
                                        Species ReactivityHuman,Mouse,Rat
                                                                                                                         Immunogen DescA synthetic peptide of human Na+/K+-ATPase (NP_000692.2).
                                                                                 ConjugateUnconjugated
                                                                                 Other NamesATP1A1;ATPase Na+/K+ transporting subunit alpha 1;ATP1A;CMT2DD;HOMGSMR2
                                        Accession NoUniprot:P05023
GeneID:476
                                        Uniprot
                                        P05023
                                        
                                        Gene ID
                                        476
                                        
                                        Calculated MW74kDa/109kDa/112kDa/113kDa
                                        Sdspage MW100KDa
                                                                                 FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:500 - 1:2000
IHC	1:50 - 1:200
                             
                            
                                                                
                                    
                                    Western blot analysis of extracts of various cell lines, using Na+/K+-ATPase   antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human lung cancer using Na+/K+-ATPase Rabbit pAb.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded mouse kidney using Na+/K+-ATPase Rabbit pAb.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human liver cancer using Na+/K+-ATPase Rabbit pAb.
                                 
                                                             
                            
                                The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. 
                            
                            
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                                      et al,Macrophage membrane-mediated targeted curcumin biomimetic nanoparticles delivery for diagnosis and treatment of spinal cord injury by suppressing neuroinflammation and ferroptosis
 ,  (2024),
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