Product Detail
Product NameCD31 Rabbit mAb
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeRabbit IgG
PurificationAffinity-chromatography
ApplicationsWB IHC IP FC
Species ReactivityHuman
SpecificityCD31 Antibody detects endogenous levels of total CD31
Immunogen DescA synthesized peptide derived from human CD31
Other Namesadhesion molecule; CD31 antigen; CD31/EndoCAM; EndoCAM; PECA1; PECAM-1; PECAM-1, CD31/EndoCAM; PECAM1; Platelet endothelial cell adhesion molecule;
Accession NoUniprot:P16284
Uniprot
P16284
FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Application Details
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50
Western blot analysis of CD31 expression in THP-1 cell lysates.
Immunohistochemical analysis of paraffin-embedded human kindey, using CD31 Antibody.
PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
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