Product Detail
Product NameCD14 Rabbit mAb
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeRabbit IgG
PurificationAffinity-chromatography
ApplicationsWB IHC ICC/IF
Species ReactivityHuman
SpecificityCD14 Antibody detects endogenous levels of CD14
Immunogen DescA synthesized peptide derived from human CD14
Other NamesCD14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein;
Accession NoUniprot:P08571
Uniprot
P08571
FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Application Details
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Western blot analysis of CD14 expression in Human tonsil cell lysate.
Immunohistochemical analysis of paraffin-embedded human breast, using CD14 Antibody.
Immunofluorescent analysis of K562 cells, using CD14 Antibody.
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles.
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