Product Detail
Product NameCBR1 Rabbit mAb
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeRabbit IgG
PurificationAffinity-chromatography
ApplicationsWB IHC ICC/IF
Species ReactivityHuman
SpecificityCBR1 Antibody detects endogenous levels of total CBR1
Immunogen DescA synthesized peptide derived from human CBR1
Other Names15 hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; CBR1; CRN; NADPH dependent carbonyl reductase 1; Prostaglandin 9 ketoreductase; SDR21C1;
Accession NoUniprot:P16152
Uniprot
P16152
FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Application Details
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
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