Product Detail
Product NameHepatitis C Virus Core Antigen antibody
Host SpeciesRabbit
ClonalityPolyclonal
Purificationaffinity purified by Protein A
ApplicationsELISA
Species ReactivityHepatitis C Virus
Immunogen DescKLH conjugated synthetic peptide derived from human HCV-Core: 1-50/60
Uniprot
P26664
Gene ID
951475
Calculated MW19/21kDa
Concentration1mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
ELISA 1:5000-10000
HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008).
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