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Location： Home > Mouse Monoclonal Antibodies > Human RHO/Rhodopsin Mouse mAb

Human RHO/Rhodopsin Mouse mAb#62259

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Product Detail

Product NameHuman RHO/Rhodopsin Mouse mAb

Clone No.MR4525

Host SpeciesMouse

ClonalityMonoclonal

IsotypeIgG2a

PurificationProtein A/G purified from cell culture supernatant.

ApplicationsELISA,IHC,IF,IP

Species ReactivityHuman

Target NameRHO

Other NamesRhodopsin, OPN2, Opsin-2, RHO

Uniprot P08100

Gene ID 6010

Calculated MW39KD

Formulation0.01M PBS, pH 7.4.

StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Application Details
ELISA 1:5000-100000
Photoreceptor required for image-forming vision at low light intensity (PubMed:7846071, PubMed:8107847). Required for photoreceptor cell viability after birth (PubMed:12566452, PubMed:2215617). Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed:26200343, PubMed:28524165, PubMed:28753425, PubMed:8107847). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:26200343, PubMed:28524165).

If you have published an article using product 62259, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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