Welcome to Sabbiotech!     
Email:info@signalwayantibody.com
Welcome Login Register My Cart(0,$0.00)
Location： Home > Mouse Monoclonal Antibodies > IL6 Mouse mAb

IL6 Mouse mAb#64432

Datasheet PDF
Availability： Yes
Total Amount:$
ADD TO CART
Detail Pictures Description Publish(0) Other
Product Detail

Product NameIL6 Mouse mAb

Clone No.MR4527

Host SpeciesMouse

ClonalityMonoclonal

IsotypeMouse IgG2b

ApplicationsWB,IHC,FC

Species ReactivityHuman,Mouse,Rat,Rabbit

Target NameIL6

Other NamesCDF;HGF;HSF;BSF2;IL-6;BSF-2;IFNB2;IFN-beta-2

Uniprot P05231

Gene ID 3569

Calculated MW24kD

FormulationPurified antibody in PBS with 0.05% sodium azide

StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Application Details
IHC 1:200-1:400
FCM 1:200-1:400
Formalin-fixed, paraffin-embedded human liver cancer tissues stained for IL6 using 64432 at 1/100 dilution in immunohistochemical analysis.
Formalin-fixed, paraffin-embedded human liver cancer tissues stained for IL6 using 64432 at 1/100 dilution in immunohistochemical analysis.
Flow Cytometry Calreticulin antibody (64432)
Flow cytometric analysis of Hela cells with IL6 Mouse mAb at 1/50 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody，red).
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).

If you have published an article using product 64432, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

QUICK NAV

New Products

Cell Signal Transduction

Cancer

Stem Cell

Neuroscience

Help and Support

Contact Us

Terms

Privacy Policy

support

Distributors