Product Detail
Product NameRecombinant Human Peroxisome proliferator-activated receptor gamma(PPARG)
Host SpeciesE.coli
PurificationGreater than 90% as determined by SDS-PAGE.
Immunogen DescExpression Region:1-477aa
Sequence Info:Full Length of Isoform 1
Other NamesNuclear receptor subfamily 1 group C member 3
Accession NoP37231
Uniprot
P37231
Gene ID
5468;
Calculated MW70.3 kDa
FormulationTris-based buffer50% glycerol
StorageThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20˚C,-80˚C. The shelf life of lyophilized form is 12 months at -20˚C,-80˚C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Tag InfoN-terminal 6xHis-SUMO-tagged
Application Details
Nuclear receptor that binds peroxisome proliferators such as hypolipidic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elents (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL,BMAL1 in the blood vessels .
If you have published an article using product AP70655, please notify us so that we can cite your literature.
15-25 business day
