Product Detail
Product NameRecombinant Human Reelin(RELN),partial
Host SpeciesE.coli
PurificationGreater than 90% as determined by SDS-PAGE.
Immunogen DescExpression Region:26-254aa
Sequence Info:Partial
Accession NoP78509
Uniprot
P78509
Gene ID
5649;
Calculated MW28.9 kDa
FormulationTris-based buffer50% glycerol
StorageThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20˚C,-80˚C. The shelf life of lyophilized form is 12 months at -20˚C,-80˚C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Tag InfoN-terminal 6xHis-tagged
Application Details
Extracellular domain matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it ses to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the Extracellular domains of lipoprotein receptors VLDLR and LRP8,APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation .
If you have published an article using product AP70710, please notify us so that we can cite your literature.
15-25 business day
