Product Detail
Product NameRecombinant Human 14-3-3 protein sigma(SFN)
Host SpeciesE.coli
PurificationGreater than 90% as determined by SDS-PAGE.
Immunogen DescExpression Region:1-248aa
Sequence Info:Full Length
Other NamesEpithelial cell marker protein 1Stratifin
Accession NoP31947
Uniprot
P31947
Gene ID
2810;
Calculated MW54.8 kDa
FormulationTris-based buffer50% glycerol
StorageThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20˚C,-80˚C. The shelf life of lyophilized form is 12 months at -20˚C,-80˚C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Tag InfoN-terminal GST-tagged
Application Details
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt,mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53,TP53.
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15-25 business day
