Product Detail
Product NameRecombinant Human Tescalcin(TESC)
Host SpeciesE.coli
PurificationGreater than 90% as determined by SDS-PAGE.
Immunogen DescExpression Region:2-214aa
Sequence Info:Full Length
Other NamesTescalcin ;TSC
Accession NoQ96BS2
Uniprot
Q96BS2
Gene ID
54997;
Calculated MW40.6 kDa
FormulationTris-based buffer50% glycerol
StorageThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20˚C,-80˚C. The shelf life of lyophilized form is 12 months at -20˚C,-80˚C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Tag InfoN-terminal 6xHis-SUMO-tagged
Application Details
Functions as an integral cofactor in cell pH regulation by controlling plasma mbrane-type Na+,H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1,NHE1 at the plasma mbrane. Promotes the induction of hatopoietic st cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
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