Product Detail
Product NameHSP70 Antibody HRP Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsWB IHC-P IHC-F ICC
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 480-530 641 derived from human HSP70
Target NameHSP70
ConjugateHRP
Excitation EmissionN A
Other NamesHSP72; HSPA1; HSP7I; HSP7-1; HSP7-1A; HEL-S-13; Heat shock 7 kDa protein 1A 1B; Heat shock 7 kDa protein 1 2; HSP7-1 HSP7-2; HSP7.1 HSP7.2; HSPA1A; HSX7
Accession NoSwiss-Prot#P08107
NCBI Gene ID3303
Uniprot
P08107
Gene ID
3303;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
In cooperation with other chaperones, Hsp7s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
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