Product Detail
Product NameHistone H4K20me1 Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen TypePeptide
Immunogen DescA synthetic peptide of human MonoMethyl-Histone H4-K20
Target NameHistone H4
ConjugateUnconjugated
Other NamesFO108;H4;H4/n;H4F2;H4FN;HIST2H4;Histone H4;HIST1H4A;HIST2H4A
Accession NoUniprot:P62805
GeneID:8370
Uniprot
P62805
Gene ID
8370
Sdspage MW11KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MonoMethyl-Histone H4-K20 antibody.
Immunohistochemistry of paraffin-embedded rat testis using MonoMethyl-Histone H4-K20 antibody.
Immunofluorescence analysis of 293T cells using MonoMethyl-Histone H4-K20 antibody.
Immunohistochemistry of paraffin-embedded human colon using MonoMethyl-Histone H4-K20 antibody.
Immunohistochemistry of paraffin-embedded mouse testis using MonoMethyl-Histone H4-K20 antibody.
Western blot analysis of extracts of various cell lines, using MonoMethyl-Histone H4-K20 antibody.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
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