Product Detail
Product NameHistone H3 (Malonyl-K57) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
ApplicationsWB
Species ReactivityHuman
SpecificityHistone H3(Malonyl-K57) Antibody detects endogenous levels of Histone H3 only
when malonylated at K57.
Immunogen DescA synthesized peptide derived from human Histone H3 around the malonylated site of K57.
ConjugateUnconjugated
Other NamesHistone H3/a
Histone H3/b
Histone H3/c
Histone H3/d
Histone H3/f
Histone H3/h
Histone H3/i
Histone H3/j
Histone H3/k
Histone H3/l
Uniprot
P68431
Gene ID
8350;8351;8352;8353;8354;8355;8356;8357;8358;8968;
Sdspage MW15kDa
Concentration1 mg/ml
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM
NaCl,0.02% sodium azide and 50% glycerol.
StorageStore at --20˚C/1 year
Application Details
Western Blot: 1/500 - 1/2000
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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