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Estrogen Receptor-a(Phospho-Ser118) Antibody #11072

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameEstrogen Receptor-a(Phospho-Ser118) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu
  • SpecificityThe antibody detects endogenous level of Estrogen Receptor-aonly when phosphorylated at serine 118.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 118 (Q-L-S(p)-P-F) derived from Human Estrogen Receptor-a.
  • Target NameEstrogen Receptor-a
  • ModificationPhospho
  • Alternative Names    ER; ESR; ESR1; ESTR; ESTRA
  • Uniprot P03372
  • Gene ID 2099;
  • Accession No. Swiss-Prot: P03372
    NCBI Protein: NP_000116.2
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Adiponectin Attenuates Streptozotocin-Induced Tau Hyperphosphorylation and Cognitive Deficits by Rescuing PI3K/Akt/GSK-3β Pathway. In Neurochem Res.On 2018 Feb by Xu ZP, Gan GS et al..PMID: 29098530, , (2018),
PMID: 29098530
Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models.In Breast Cancer Res on 2017 May 23 by Amir Bahreini , Zheqi Li,et al..PMID: 28535794, , (2017),
PMID: 28535794
ESR1 Ligand-Binding Domain Mutations in Hormone-Resistant Breast Cancer. In Nat Genet on 2013 Dec. In Nat Genet on 2013 Dec by Weiyi Toy , Yang Shen, et al..PMID:24185512, , (2013),
PMID: 24185512
Identification of DNA sequence variants in the estrogen receptor pathway in breast cancer. In Biochem Biophys Res Commun on 2005 Nov 4 by Zhaoyi Wang, Xintian Zhang,et al..PMID:16165085, , (2005),
PMID: 16165085
Please let us know if you have published research using #11072 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep