• Product NameELP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB, IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ELP1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human ELP1
• Target NameELP1
• Alternative Names    FD; DYS; IKAP; IKI3; TOT1; IKBKAP
• Accession No. Swiss-Prot#:O95163
  NCBI Gene ID:8518
  Gene Accssion:NP_003631
• UniprotO95163
• Gene ID8518;
• Calculated MW 150 kDa
• Concentration 0.7
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• WB dilution:1:200-1000
  IHC dilution:1: 25-100
  

The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 231, K562 and A172 cell lysates, Primary antibody:47649(ELP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
• The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 47649(ELP1 Antibody) at dilution 1/25.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting