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DNA PKcs(Phospho-Thr2609) Antibody #11167

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
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Description
  • Product NameDNA PKcs(Phospho-Thr2609) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu
  • SpecificityThe antibody detects endogenous level of DNA PKcs only when phosphorylated at threonine 2609.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 2609 (V-E-T(p)-Q-A) derived from Human DNA-PK.
  • Target NameDNA PKcs
  • ModificationPhospho
  • Alternative Names    DNPK1; PRKD; PRKDC; XRCC7; P460
  • Accession No. Swiss-Prot: P78527
    NCBI Protein: NP_001075109.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Li Xia,Kang Qin,Xin-Ran Wang,Xiao-Ling Wang,Ai-Wu Zhou,Guo-Qiang Chen,Ying Lu Pyruvate Kinase M2 Phosphorylates H2AX and Promotes Genomic Instability in Human Tumor Cells, Oncotarget, 2017 Nov 17;8(65):109120-109134. (2017),
PMID: 29312595
Please let us know if you have published research using #11167 so that we can cite your reference.

Customer Reviews and Rankings

Anonymous user 05-14-2014 10:07:54

Hi,
Can I use it against mouse cells?

Please, let me know ASAP.
Thanks,
OM

AdministratorHi OM. Thanks for your inquiry. Sorry for late reply. The antigen is a peptide from human protein and has 77% of homology with mouse. The antibody has not been validated on mouse cells.

Anonymous user 05-14-2014 10:07:42

Hi,
Can I use it against mouse cells?

Please, let me know ASAP.
Thanks,
OM

AdministratorHi OM. Thanks for your inquiry. Sorry for late reply. The antigen is a peptide from human protein and has 77% of homology with mouse. The antibody has not been validated on mouse cells.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep