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Enzymes

DNA PKcs(Phospho-Thr2609) Antibody #11167

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameDNA PKcs(Phospho-Thr2609) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu
  • SpecificityThe antibody detects endogenous level of DNA PKcs only when phosphorylated at threonine 2609.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 2609 (V-E-T(p)-Q-A) derived from Human DNA-PK.
  • Target NameDNA PKcs
  • ModificationPhospho
  • Alternative Names    DNPK1; PRKD; PRKDC; XRCC7; P460
  • Accession No. Swiss-Prot: P78527
    NCBI Protein: NP_001075109.1
  • UniprotP78527
  • Gene ID5591;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Pyruvate Kinase M2 Phosphorylates H2AX and Promotes Genomic Instability in Human Tumor Cells.In Oncotarget on 2017 Nov 17 by Li Xia, Kang Qin,et al..PMID: 29312595, , (2017),
PMID: 29312595
Please let us know if you have published research using #11167 so that we can cite your reference.

Customer Reviews and Rankings

Anonymous user 05-14-2014 10:07:54

Hi,
Can I use it against mouse cells?

Please, let me know ASAP.
Thanks,
OM

AdministratorHi OM. Thanks for your inquiry. Sorry for late reply. The antigen is a peptide from human protein and has 77% of homology with mouse. The antibody has not been validated on mouse cells.

Anonymous user 05-14-2014 10:07:42

Hi,
Can I use it against mouse cells?

Please, let me know ASAP.
Thanks,
OM

AdministratorHi OM. Thanks for your inquiry. Sorry for late reply. The antigen is a peptide from human protein and has 77% of homology with mouse. The antibody has not been validated on mouse cells.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep