• Product NameGUCY1B3 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human GUCY1B3 (NP_000848.1).
• Alternative Names    GUCY1B3; GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1; guanylate cyclase soluble subunit beta-1
• Accession No. Swiss-Prot#:Q02153
  NCBI Gene ID:2983
• UniprotQ02153
• Gene ID2983;
• Calculated MW 70kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:200 - 1:2000
  IHC 1:50 - 1:200

This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.

• Western blot analysis of extracts of various cell lines, using GUCY1B3 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting