• Product NameDARS2 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human DARS2 (NP_060592.2).
• Alternative Names    DARS2; ASPRS; LBSL; MT-ASPRS; aspartate--tRNA ligase, mitochondrial
• Accession No. Swiss-Prot#:Q6PI48
  NCBI Gene ID:55157
• UniprotQ6PI48
• Gene ID55157;
• Calculated MW 74kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).

• Western blot analysis of extracts of various cell lines, using DARS2 at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded human liver damage using DARS2 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human lung cancer using DARS2 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human stomach using DARS2 at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting