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Enzymes

PERK (Phospho-Thr 982) Antibody #12814

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
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Description
  • Product NamePERK (Phospho-Thr 982) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAffinity purification using immunogen.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • Specificityp-PERK (Phospho-Thr 982) Antibody detects endogenous levels of total p-PERK at Thr 982.
  • Immunogen TypePeptide
  • Immunogen DescriptionA synthesized peptide derived from human PERK around the phosphorylation site of Thr982.
  • Target Namep-PERK (Phospho-Thr 982)
  • ModificationPhospho
  • Alternative Names    EIF2AK3, HRI, HsPEK, Pancreatic eIF2-alpha kinase, PEK, PERK, PKR-like ER kinase, WRS
  • Accession No. Swiss-Prot#: Q9NZJ5
    NCBI Gene ID: 9451
  • UniprotQ9NZJ5
  • Gene ID9451;
  • Target Species human
  • Calculated MW 125 kDa
  • Concentration 1.0mg/mL
  • Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

Published Papers

Activation of ROS-PERK-TFEB by filbertone ameliorates neurodegenerative diseases via enhancing the autophagy-lysosomal pathwayIn J Nutr BiochemOn2023 AugbyJeongmin Park , Jeong Heon Gong et al..PMID:36958418, , (2023),
PMID: 36958418
Malondialdehyde-Acetaldehyde Extracellular Matrix Protein Adducts Attenuate Unfolded Protein Response During Alcohol and Smoking�CInduced Pancreatitis. In Gastroenterology on 2022 Oct by Rakesh Bhatia, Christopher M Thompson, et al..PMID: 35788346, , (2022),
PMID: 35788346
PERK activation by SB202190 ameliorates amyloidogenesis via the TFEB-induced autophagy-lysosomal pathway. In Aging (Albany NY) on 2022 Feb 15 by Mihyang Do, Jeongmin Park, et al..PMID:35166693, , (2022),
PMID: 35166693
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer. In Int J Mol Sci on 2022 Jan 25 by Meiyu Cheng, Huimei Yu, et al..PMID: 35163244, , (2022),
PMID: 35163244
View All Published Papers 5‑Nitro‑2‑(3‑phenylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway. In Int J Mol Med on 2021 Apr by Lingzhi Niu, Xin Liu,et al..PMID:33604681, , (2021),
PMID: 33604681
γ-Glutamylcysteine Alleviates Ischemic Stroke-Induced Neuronal Apoptosis by Inhibiting ROS-Mediated Endoplasmic Reticulum Stress. In Oxid Med Cell Longev on 2021 Nov 16 by Hui-Qin Li, Sheng-Nan Xia, et al..PMID:34824669, , (2021),
PMID: 34824669
PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEBinduced Autophagy-Lysosomal Pathway, , (2021),
PMID:
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway. In Brain Res Bull on 2020 Sep by Yi Liu, Di Wen, et al..PMID:32544512, , (2020),
PMID: 32544512
Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury. In Aging (Albany NY) on 2020 Aug 28 by Jing-Yao Song, Bin Fan,et al..PMID: 32858529, , (2020),
PMID: 32858529
Deficiency of fibroblast growth factor 21 aggravates obesity-Induced atrophic responses In skeletal muscle. In J Inflamm (Lond) on 2019 Jul 4 by Kim CS, Joe Y, et al..PMID:31312114, , (2019),
PMID: 31312114
High glucose and bupivacaIne?Induced cytotoxicity is mediated by enhanced apoptosis and impaired autophagy via the PERK?ATF4?CHOP and IRE1?TRAF2 signalIng pathways. In Mol Med Rep on 2019 Sep by Liu Y, Sun L, et al..PMID:31524237, , (2019),
PMID: 31524237
Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury.In Cell Death Dis. On 2018 Oct 17 by Kim HJ, Joe Y et al..PMID: 30333475, , (2018),
PMID: 30333475
Carbon Monoxide Protects Against Hepatic Steatosis in Mice by Inducing sestrin-2 via the PERK-eIF2α-ATF4 Pathway.In Free Radic Biol Med on 2017 Sep by Hyo Jeong Kim, Yeonsoo Joe,et al..PMID: 28578014, , (2017--31),
PMID: 28578014
Carbon Monoxide Protects Against Hepatic Steatosis in Mice by Inducing sestrin-2 via the PERK-eIF2α-ATF4 Pathway.In Free Radic Biol Med on 2017 Sep by Hyo Jeong Kim, Yeonsoo Joe,et al..PMID: 28578014, , (2017),
PMID: 28578014
Magnesium Isoglycyrrhizinate Promotes the Activated Hepatic Stellate Cells Apoptosis via Endoplasmic Reticulum Stress and Ameliorates Fibrogenesis in Vitro and in Vivo.In Biofactors on 2017 Nov by Mianli Bian , Xingran Chen,et al..PMID: 29048780, , (2017),
PMID: 29048780
Quercetin Stimulates Mitochondrial Apoptosis Dependent on Activation of Endoplasmic Reticulum Stress in Hepatic Stellate Cells .In Pharm Biol. On 2016 Dec by Liwei He , Xianbang Hou et al..PMID:27572285 , , (2016),
PMID: 27572285
Please let us know if you have published research using #12814 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep