• Product NameSTEAP3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms Rt
• SpecificityThis STEAP3 antibody does not cross-react with other STEAP proteins.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 15 amino acid peptide from near the amino terminus of human STEAP3.
• Target NameSTEAP3
• Alternative Names    Six transmembrane epithelial antigen of prostate 3, dudulin-2
• Accession No. Swiss-Prot:Q658P3
  Gene ID:55240
• UniprotQ658P3
• Gene ID55240;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.

• Western blot analysis of STEAP3 in rat liver tissue lysate with STEAP3 antibody at (A) 1 and (B) 2 ug/mL.
• Immunohistochemistry of STEAP3 in mouse liver tissue with STEAP3 antibody at 2.5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting