• Product NameTCC52 Antibody
• Host SpeciesChicken
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB ICC
• Species ReactivityHu Ms Rt
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 15 amino acid peptide near the carboxy terminus of human TCC52.
• Target NameTCC52
• Alternative Names    Testis cancer centrosome-related protein 52, DDB1 and CUL4 associated factor 12, DCAF12, CT102, WDR40A
• Accession No. Swiss-Prot:Q5T6F0
  Gene ID:25853
• UniprotQ5T6F0
• Gene ID25853;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.

• Western blot analysis of TCC52 in 293 cell lysate with TCC52 antibody at 1 ug/mL.
• Immunocytochemistry of TCC52 in 293 cells with TCC52 antibody at 2.5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting