• Product NameGluR2 (Phospho-Ser880) antibody
• Brief DescriptionRabbit Polyclonal
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using phospho-peptide and non-phospho-peptide.
• ApplicationsWB, IHC
• Species ReactivityHuman, Mouse, Rat
• SpecificityThis antibody detects endogenous levels of human GluR2 when phosphorylated at serine 880.
• Immunogen TypePeptide
• Immunogen Descriptionpeptide derived from GRIA2, corresponding to amino acid residues around phosphorylated Ser880.
• Target NameGluR2
• UniprotP42262
• Gene ID2891
• Calculated MW 99kDa
• Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Storage Store at +4˚C for short term. Store at -20˚C for long term. Avoid freeze/thaw cycle.

• WB 1:500-1:2000, IHC 1:50-1:200

GluR2 an integral membrane protein belonging to the glutamate-gated ion channel family. L-glutamate (Glu) acts as an excitatory neurotransmitter at many synapses in the central nervous system. Glutamate receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.

• Formalin-fixed, paraffin-embedded human brain tissue stained for Phospho-GluR2 (S880) at 1/100 dilution in immunohistochemical analysis.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting