• Product NameBAD Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total BAD protein
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human BAD.
• Target NameBAD
• Alternative Names    BAD; BBC6; BCL2L8; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6
• Accession No. Swiss-Prot: Q92934
  NCBI Gene ID: 572
• UniprotQ92934
• Gene ID572;
• SDS-PAGE MW 18kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 By similarity. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Wang H.-G., Cell 87:629-638(1996).
Ottilie S., J. Biol. Chem. 272:30866-30872(1997).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using BAD antibody #33154.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting