• Product NameLAT3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total LAT3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human LAT3.
• Target NameLAT3
• Alternative Names    L-type amino acid transporter 3; LAT3; large neutral amino acids transporter small subunit 3; prostate cancer overexpressed gene 1 protein; solute carrier family 43 member 1
• Accession No. Swiss-Prot: O75387
  NCBI Gene ID: 8501
• UniprotO75387
• Gene ID8501;
• SDS-PAGE MW 61kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.

Cole K.A., Genomics 51:282-287(1998).
Babu E., J. Biol. Chem. 278:43838-43845(2003).
Chuaqui R.F., Urology 50:302-307(1997).

• Western blot analysis of extracts from Jurkat cells and A549 cells, using LAT3 antibody #33609.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting