• Product NameADA2L Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total ADA2L protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ADA2L.
• Target NameADA2L
• Alternative Names    Transcriptional adapter 2-like; ADA2-like protein; TADA2L; KL04P;
• Accession No. Swiss-Prot: O75478
  NCBI Gene ID: 6871
• UniprotO75478
• Gene ID6871;
• SDS-PAGE MW 47kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site By similarity. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.

Candau R., Mol. Cell. Biol. 16:593-602(1996).
Ogryzko V.V., Cell 94:35-44(1998).
Henriksson A., Mol. Cell. Biol. 17:3065-3073(1997).

• Western blot analysis of extracts from COS-7 cells and COLO205 cells, using ADA2L antibody #33614.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting