• Product NameAP2C Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total AP2C protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human AP2C.
• Target NameAP2C
• Alternative Names    AP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1;
• Accession No. Swiss-Prot: Q92754
  NCBI Gene ID: 7022
• UniprotQ92754
• Gene ID7022;
• SDS-PAGE MW 45kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

Williamson J.A., Genomics 35:262-264(1996).
McPherson L.A., Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997).
Deloukas P., Nature 414:865-871(2001).

• Western blot analysis of extracts from HepG2 cells and HUVEC cells, using AP2C antibody #34004.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting