• Product Name5-HT-1F Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total 5-HT-1F protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human 5-HT-1F.
• Target Name5-HT-1F
• Alternative Names    5-hydroxytryptamine receptor 1F; 5-HT-1F; Serotonin receptor 1F; HTR1F; HTR1EL
• Accession No. Swiss-Prot: P30939
  NCBI Gene ID: 3355
• UniprotP30939
• Gene ID3355;
• SDS-PAGE MW 38kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Lovenberg T.W., Proc. Natl. Acad. Sci. U.S.A. 90:2184-2188(1993).
Adham N., Proc. Natl. Acad. Sci. U.S.A. 90:408-412(1993).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

• Western blot analysis of extracts from COS-7 cells, using 5-HT-1F antibody #34150.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting