• Product NameCytochrome P450 26A1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total Cytochrome P450 26A1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human Cytochrome P450 26A1.
• Target NameCytochrome P450 26A1
• Alternative Names    Cytochrome P450 26A1; EC 1.14.-.-; Retinoic acid-metabolizing cytochrome; P450 retinoic acid-inactivating 1; P450RAI
• Accession No. Swiss-Prot: O43174
  NCBI Gene ID: 1592
• UniprotO43174
• Gene ID1592;
• SDS-PAGE MW 56kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.

White J.A., J. Biol. Chem. 272:18538-18541(1997).
Sonneveld E., Cell Growth Differ. 9:629-637(1998).
ova-Griffin M.E., Biochem. Biophys. Res. Commun. 252:487-491(1998).

• Western blot analysis of extracts from HepG2 cells, HeLa cells and 293 cells, using Cytochrome P450 26A1 antibody #34230.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting