• Product NameSCNN1D Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SCNN1D protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SCNN1D.
• Target NameSCNN1D
• Alternative Names    Amiloride-sensitive sodium channel subunit delta; Epithelial Na(+) channel subunit delta; Delta-ENaC; SCNED; Nonvoltage-gated sodium channel 1 subunit delta
• Accession No. Swiss-Prot: P51172
  NCBI Gene ID: 6339
• UniprotP51172
• Gene ID6339;
• SDS-PAGE MW 70kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Waldmann R., J. Biol. Chem. 270:27411-27414(1995).
Ota T., Nat. Genet. 36:40-45(2004).
Gregory S.G., Nature 441:315-321(2006).

• Western blot analysis of extracts from Raji cells(serum starvation treatment), using SCNN1D Antibody. The lane on the left was treated with blocking peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting