• Product NameATN1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total ATN1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from N-terminal of human ATN1.
• Target NameATN1
• Alternative Names    ATN1; Atrophin-1; Dentatorubral-pallidoluysian atrophy protein; DRPL;
• Accession No. Swiss-Prot: P54259
  NCBI Gene ID: 1822
• UniprotP54259
• Gene ID1822;
• SDS-PAGE MW 130kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation By similarity. Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.

Nagafuchi S., Nat. Genet. 8:177-182(1994).
Onodera O., Am. J. Hum. Genet. 57:1050-1060(1995).
Margolis R.L., Brain Res. Mol. Brain Res. 36:219-226(1996).

• Western blot analysis of extracts from HeLa cells, A549 cells, K562 cells, COLO205 cells and NIH-3T3 cells, using ATN1 antibody #34473.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting