• Product NameABCC3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ABCC3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ABCC3.
• Target NameABCC3
• Alternative Names    Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3
• Accession No. Swiss-Prot: O15438
  NCBI Gene ID: 8714
• UniprotO15438
• Gene ID8714;
• SDS-PAGE MW 170kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes By similarity.

Uchiumi T., em. Biophys. Res. Commun. 252:103-110(1998).
Kiuchi Y., FEBS Lett. 433:149-152(1998).
linsky M.G., J. Natl. Cancer Inst. 90:1735-1741(1998).

• Western blot analysis of extracts from HeLa cells, A549 cells, Jurkat cells, HuvEc cells, K562 cells and HepG2 cells, using ABCC3 antibody #34527.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting