• Product NameC1S Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total C1S protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human C1S.
• Target NameC1S
• Alternative Names    28S ribosomal protein S7; mitochondrial; S7mt; MRP-S7; bMRP27a
• Accession No. Swiss-Prot: P09871
  NCBI Gene ID: 716
• UniprotP09871
• Gene ID716;
• SDS-PAGE MW 77kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

McKinnon C.M., Eur. J. Biochem. 169:547-553(1987).
Tosi M., Biochemistry 26:8516-8524(1987).
Kusumoto H., Proc. Natl. Acad. Sci. U.S.A. 85:7307-7311(1988).

• Western blot analysis of extracts from Jurkat cells and COLO cells, using C1S antibody #34610.
• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using C1S antibody #34610.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting