• Product NameEFEMP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Rt
• SpecificityThe antibody detects endogenous levels of total EFEMP1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human EFEMP1.
• Target NameEFEMP1
• Alternative Names    EGF-containing fibulin-like extracellular matrix protein 1; Fibulin-3; FIBL-3; Fibrillin-like protein; Extracellular protein S1-5
• Accession No. Swiss-Prot: Q12805
  NCBI Gene ID: 2202
• UniprotQ12805
• Gene ID2202;
• SDS-PAGE MW 55kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

Lecka-Czernik B., Mol. Cell. Biol. 15:120-128(1995).
Ikegawa S., Genomics 35:590-592(1996).
Giltay R., Matrix Biol. 18:469-480(1999).

• Western blot analysis of extracts from rat lung cells, using EFEMP1 antibody #34665.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting