• Product NameGDF15 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total GDF15 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human GDF15.
• Target NameGDF15
• Alternative Names    GDF-15; growth differentiation factor 15; MIC-1; MIC1; NAG-1
• Accession No. Swiss-Prot: Q99988
  NCBI Gene ID: 9518
• UniprotQ99988
• Gene ID9518;
• SDS-PAGE MW 37kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]

Hromas R., Biochim. Biophys. Acta 1354:40-44(1997).
Yokoyama-Kobayashi M., J. Biochem. 122:622-626(1997).
Bootcov M.R., Proc. Natl. Acad. Sci. U.S.A. 94:11514-11519(1997).

• Western blot analysis of extracts from HepG2 cells and 293 cells, using GDF15 antibody #34712.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting