• Product NamePTRF Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total PTRF protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human PTRF.
• Target NamePTRF
• Alternative Names    CAVIN; Cavin-1; CGL4; FKSG13; FLJ90031
• Accession No. Swiss-Prot: Q6NZI2
  NCBI Gene ID: 284119
• UniprotQ6NZI2
• Gene ID284119;
• SDS-PAGE MW 43kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.

Wang Y.-G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Jansa P., EMBO J. 17:2855-2864(1998).
Aboulaich N., Biochem. J. 383:237-248(2004).

• Western blot analysis of extracts from HeLa cells and A549 cells, using PTRF antibody #35182.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting