• Product NameCC14A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CC14A protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human CC14A.
• Target NameCC14A
• Alternative Names    CC14A; CDC10 (cell division cycle 10; S. cerevisiae; homolog); cdc14
• Accession No. Swiss-Prot: Q9UNH5
  NCBI Gene ID: 8556
• UniprotQ9UNH5
• Gene ID8556;
• SDS-PAGE MW 66kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.

Li L., J. Biol. Chem. 272:29403-29406(1997).
Wong A.K.C., Genomics 59:248-251(1999).
Gregory S.G., Nature 441:315-321(2006).

• Western blot analysis of extracts from HeLa cells, using CC14A antibody #35243.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting