• Product NameSTK10 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total STK10 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human STK10.
• Target NameSTK10
• Alternative Names    kinase GEK2; LOK; Lymphocyte-oriented kinase; Serine/threonine protein kinase 10; STK10
• Accession No. Swiss-Prot: O94804
  NCBI Gene ID: 6793
• UniprotO94804
• Gene ID6793;
• SDS-PAGE MW 120kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.

Kuramochi S., Immunogenetics 49:369-375(1999).
Ota T., Nat. Genet. 36:40-45(2004).
Schmutz J., Nature 431:268-274(2004).

• Western blot analysis of extracts from HeLa cells and HuvEc cells, using STK10 antibody #35288.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting