• Product NamePARD6A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PARD6A protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to residues near the C terminal of human par-6 family cell polarity regulator alpha
• Target NamePARD6A
• Alternative Names    PAR6; PAR6C; TAX40; PAR-6A; TIP-40; PAR6alpha
• Accession No. Swiss-Prot#: Q9NPB6
  NCBI Gene ID: 50855
  Gene Accssion: BC015626
• UniprotQ9NPB6
• Gene ID50855;
• Concentration 3mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:50-1:200

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #35868 at dilution 1/60.
• Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #35868 at dilution 1/60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting