• Product NameMASP2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total MASP2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human MASP2.
• Target NameMASP2
• Alternative Names    Mannan-binding lectin serine protease 2; Mannose-binding protein-associated serine protease 2; MASP-2; MBL-associated serine protease 2;
• Accession No. Swiss-Prot: O00187
  NCBI Gene ID: 10747
• UniprotO00187
• Gene ID10747;
• SDS-PAGE MW 75kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.

Thiel S., Nature 386:506-510(1997).
Takahashi M., Int. Immunol. 11:859-863(1999).
Stover C.M., J. Immunol. 162:3481-3490(1999).

• Western blot analysis of extracts from K562 cell, using MASP2 antibody #34775.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting